Tampa Bay at Atlanta Sun. September 21 @ 1:00pm ET on Fox

Summary: Bitter NFC South rivals with plenty of defensive ammunition.

Hot Tip: Warrick Dunn is the key to Atlanta coming out of this one with a W.

Both of these teams are coming off extremely difficult home-opening losses and look to avenge those losses this week. Tampa Bay was embarrassed by Carolina last week. Their top-notch defense will take it a notch even higher this week and that could be bad news for Doug Johnson. He didn't look good at all against Washington last week. He'll need to turn that around to avoid seeing Michael Vick and his boot take over at half-time. This one will definitely showcase the defenses on either side. Pay close attention to see which offense gets the ball going enough to pull it out.

Summary: Bitter AFC West rivals with plenty of offensive ammunition.

Hot Tip: If he plays, this will be most of the country’s first look at Jake Plummer in a Broncos uniform. We’ll all get to see exactly where he's hurting and where he's not.

These two teams both have a lot of question marks. Even in week 3, both teams will be looking at this game to define who’s going to have the upper hand in this closely contested division. Keep an eye on Clinton Portis’ health. He's listed as Probable (Chest) while Plummer is listed as Questionable (Shoulder). Even though Mike Anderson is a fully equipped backup, Portis is the man that’s expected to take this team all the way this year.