Too many people are sleeping on Charles. There's just no reason to be comparing his situation to AP's -- four months seperated their injuries (which is huge) and Charles is almost two years younger. With the recent injury to Matthews, I think Charles moves up to the 7th RB (soon to be 6th if MJD doesn't report in the next week or two). My current list sits something like this:
MJD* (pending holdout and could move up or down)
Steven Jackson (who seemingly everyone is leaving out, but a guy I'd absolutely love in the 3rd round)
Lynch* (pending legal issues, so he could move up or down potentially)
Matthews (throwing him here now, but this was my knee jerk reaction this morning)
Sproles is obviously a wild card depending on your format, but I think after that group, I'd finish picking off any of the top-10 WRs or so before I grabbed guys like Fred Jackson, Turner, Richardson, AP, Bradshaw, Gore...