Strength of schedule is calculated from the opponents projected fantasy points allowed for the WR position. The best rating is +16 which gives the player the advantage against the defense and indicates an easy opponent, the worst rating is -16 which gives the defense the advantage and indicates a tough opponent.
Manningham is coming of both ACL and PCL reconstruction and has fallen behind Anquan Boldin and will have to battle a plethora of receivers for playing time. He’s expected to be ready by the start of the season just don’t expect much.