Le’Veon Bell, Pittsburgh (at Kansas City)
Ezekiel Elliott, Dallas (BYE)
LeSean McCoy, Buffalo (BYE)
Devonta Freeman, Atlanta (vs. Miami)
Kareem Hunt, Kansas City (vs. Pittsburgh)
Todd Gurley, Los Angeles Rams (at Jacksonville)
Leonard Fournette, Jacksonville (vs. Los Angeles Rams)
Melvin Gordon, San Diego (at Oakland)
SPOT START OF THE WEEK
Elijah McGuire, New York Jets (vs. New England)
The Jets are banged up at running back – so much so that it may well be McGuire who serves as the team’s lead back Sunday against the Pats. Head coach Todd Bowles told Dan Popper of the New York Daily News that the youngster’s up to the task. “It’ll be the next man up,” Bowles said. “Obviously we got everything in right now (as an offense), so Eli will carry the load and we’ll go from there. But it’s early in the week, so we’ll see how they progress.”
McGuire’s shown flashes when given the chance this season, including 131 total yards and a touchdown two weeks ago against the Jacksonville Jaguars. If he’s the last man standing in the backfield this week it could mean a great stat line against the Patriots – their defense doesn’t look like it could stop a high school team right now.
ROLL THEM OUT
Jay Ajayi, Miami (at Atlanta)
I can’t believe I’m advocating starting any Dolphins player on purpose. I’m even sober and everything. It may not be saying a whole lot, but Ajayi is probably Miami’s best offensive weapon, and the Falcons are allowing the seventh-most fantasy points to tailbacks in 2017. What do you want? I’m trying to find some positives here!
Mike Gillislee, New England (at New York Jets)
Scott Levine of the Clinton Herald agrees that Gillislee is a solid fantasy start against the Jets Sunday. “The New England backfield has plenty of mouths to feed,” he said. “When it comes to rushing between the tackles, though, Gillislee is the main answer. That should work well in this week 6 tilt against a Jets defense giving up 143 yards per game on the ground.”
Chris Thompson, Washington (vs. San Francisco)
The Redskins are fresh off their bye week, but the playing status of starting tailback Rob Kelley for Week 6 remains in doubt. If Kelley can’t go this could be a great chance for Thompson to rebound from a down Week 4 against a San Francisco 49ers team giving up more points to running backs than any team not named the Los Angeles Rams.
SIT THEM DOWN
Aaron Jones, Green Bay (at Minnesota)
After gashing the Dallas Cowboys for 125 yards and a touchdown on 19 carries last week, Jones is the toast of fantasy football. But folks who rush the youngster back out there in Week 6 are begging for a letdown. Not only might Ty Montgomery be back, but the Vikings are exponentially better at defending the run than the Cowboys.
Doug Martin, Tampa Bay (vs. Arizona)
Martin played pretty well in his first game action of 2017 last week against the New England Patriots, picking up 74 yards on 13 carries and finding the end zone. That came against the worst defense in the National Football League though – the Cardinals have been much stingier (27th in fantasy points allowed) to fantasy running backs than the Pats.